2026
33. Shi, Y., Li, H., Liu, P., Bunick, C.G., Tang, S., Wang, J., Batista, V.S. (2026) Humanized anti-PD-1 antibodies generated using the conditional kernel-elastic autoencoder. bioRxiv 2026.08.03.742579. PMCID: PMC13484611. PMID: 42620315. [PDF]
32. Li, Y., Zheng, W., Leem, J., Wu, C., Tang, S., Mogessie, B., Xiong, Y. (2026) Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs. Nat Struct Mol Biol. Online ahead of print. PMCID: PMC13441485. PMID: 42426369. [PDF]
31. Madheshiya, P.K., Henry, S., Chen, X., Doak, N., Gierke, T.R., Tang, S., Wang, J., Didychuk, A.L. (2026) Kaposi’s sarcoma-associated herpesvirus uses a novel protein fold to hijack RNA polymerase II for viral late gene transcription. bioRxiv 2026.06.29.734287. PMCID: PMC13345323. PMID: 42427571. [PDF]
30. Gierke, T.R., Liu, P., Lu, Y., Tang, S. (2026) Membrane fusions during mammalian fertilization. In: Weiler, J., Sieler, M., Dittmar, T. (eds) Cell Fusion. Adv Exp Med Biol 1509. Springer, pp 87-106. PMID: 42168739. [PDF]
29. Liu, P., Castelino, R.E., Gierke, T.R., Wood, A.J., Lu, Y., Tang, S. (2026) Structure and inhibition of the sperm TMEM95-FIMP complex in mammalian fertilization. bioRxiv 2026.05.14.724122. PMCID: PMC13192804. PMID: 42182310. [PDF] [Github]
28. Wood, A.J., Liu, P., Tang, S. (2026) A molecular lattice reinforces the sperm head-tail junction. Proc Natl Acad Sci U S A 123(20):e2608469123. PMCID: PMC13187801. PMID: 42114004. [PDF]
27. Chang, H.-Y., Gierke, T.R., Tang, S., Lu, Y. (2026) Molecular interplay between sperm and oocyte: a narrative review. Hum Reprod Update 32(4):409-439. PMCID: PMC13319360. PMID: 41884958. [PDF]
26. Shi, Y., Kim, Y., Liu, P., Wang, J., Tang, S., Batista, V.S. (2026) Computational evolution of anti–PD-1 antibodies induces structural refolding for high-affinity interactions. Biochemistry 65(5):517-520. PMID: 41671420. [PDF]
2025
25. Filsinger Interrante, M.V., Tang, S., Kim, S., Shanker, V.R., Hie, B.L., Bruun, T.U.J., Wu, W., Pak, J.E., Fernandez, D., Kim, P.S. (2025) Utilizing machine learning to improve neutralization potency of an HIV-1 antibody targeting the gp41 N-heptad repeat. ACS Chem Biol 20(7):1470-1480. PMCID: PMC12281478. PMID: 40540236. [PDF]
24. Lu, Y., Ikawa, M., Tang, S. (2025) Allosteric inhibition of the IZUMO1–JUNO fertilization complex by the naturally occurring antisperm antibody OBF13. Proc Natl Acad Sci U S A 122(10):e2425952122. PMCID: PMC11912406. PMID: 40042902. [PDF]
2024
23. Xu, D., Carter, J.J., Li, C., Utz, A., Weidenbacher, P.A., Tang, S., Sanyal, M., Pulendran, B., Barnes, C.O., Kim, P.S. (2024) Vaccine design via antigen reorientation. Nat Chem Biol 20(8):1012-1021. PMCID: PMC11247139. PMID: 38225471. [PDF]
22. Hie, B.L., Shanker, V.R., Xu, D., Bruun, T.U.J., Weidenbacher, P.A., Tang, S., Wu, W., Pak, J.E., Kim, P.S. (2024) Efficient evolution of human antibodies from general protein language models. Nat Biotechnol 42(2):275-283. PMCID: PMC10869273. PMID: 37095349. [PDF]
2023
21. Skinner, W.M., Petersen, N.T., Unger, B., Tang, S., Tabarsi, E., Lamm, J., Jalalian, L., Smith, J., Bertholet, A.M., Xu, K., Kirichok, Y., Lishko, P.V. (2023) Mitochondrial uncouplers impair human sperm motility without altering ATP content. Biol Reprod 109(2):192-203. PMCID: PMC10427809. PMID: 37294625. [PDF]
20. Abhiraman, G.C., Bruun, T.U.J., Caveney, N.A., Su, L.L., Saxton, R.A., Yin, Q., Tang, S., Davis, M.M., Jude, K.M., Garcia, K.C. (2023) A structural blueprint for interleukin-21 signal modulation. Cell Rep 42(6):112657. PMCID: PMC10320830. PMID: 37339051. [PDF]
19. Weidenbacher, P.A., Sanyal, M., Friedland, N., Tang, S., Arunachalam, P.S., Hu, M., Kumru, O.S., Morris, M.K., Fontenot, J., Shirreff, L., Do, J., Cheng, Y., Vasudevan, G., Feinberg, M.B., Villinger, F.J., Hanson, C., Joshi, S.B., Volkin, D.B., Pulendran, B., Kim, P.S. (2023) Author correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. Nat Commun 14(1):6211. PMCID: PMC10556009. PMID: 37798288.
18. Weidenbacher, P.A., Sanyal, M., Friedland, N., Tang, S., Arunachalam, P.S., Hu, M., Kumru, O.S., Morris, M.K., Fontenot, J., Shirreff, L., Do, J., Cheng, Y., Vasudevan, G., Feinberg, M.B., Villinger, F.J., Hanson, C., Joshi, S.B., Volkin, D.B., Pulendran, B., Kim, P.S. (2023) A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. Nat Commun 14(1):2149. PMCID: PMC10110616. PMID: 37069151. [PDF]
17. Bruun, T.U.J., Tang, S., Erwin, G.S., Deis, L.N., Fernandez, D., Kim, P.S. (2023) Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies. J Biol Chem 299(4):103062. PMCID: PMC10064241. PMID: 36841484. [PDF]
16. Lu, Y., Shimada, K., Tang, S., Zhang, J., Ogawa, Y., Noda, T., Shibuya, H., Ikawa, M. (2023) 1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proc Natl Acad Sci U S A 120(8):e2207263120. PMCID: PMC9974436. PMID: 36787362. [PDF]
15. Weidenbacher, P.A., Musunuri, S., Powell, A.E., Tang, S., Do, J., Sanyal, M., Kim, P.S. (2023) Simplified purification of glycoprotein-modified ferritin nanoparticles for vaccine development. Biochemistry 62(2):292-299. PMCID: PMC9850919. PMID: 35960597. [PDF]
2022
14. Tang, S., Lu, Y., Skinner, W.M., Sanyal, M., Lishko, P.V., Ikawa, M., Kim, P.S. (2022) Human sperm TMEM95 binds eggs and facilitates membrane fusion. Proc Natl Acad Sci U S A 119(40):e2207805119. PMCID: PMC9546558. PMID: 36161911. [PDF]
2021
13. Powell, A.E., Zhang, K., Sanyal, M., Tang, S., Weidenbacher, P.A., Li, S., Pham, T.D., Pak, J.E., Chiu, W., Kim, P.S. (2021) A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice. ACS Cent Sci 7(1):183-199. PMCID: PMC7805605. PMID: 33527087. [PDF]
12. Banjade, S., Shah, Y.H., Tang, S., Emr, S.D. (2021) Design principles of the ESCRT-III Vps24-Vps2 module. eLife 10. PMCID: PMC8143795. PMID: 34028356. [PDF]
2019
11. Tang, S., Kim, P.S. (2019) A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery. Proc Natl Acad Sci U S A 116(49):24500-24506. PMCID: PMC6900541. PMID: 31727844. [PDF]
10. Banjade, S., Tang, S., Emr, S.D. (2019) Genetic and biochemical analyses of yeast ESCRT. Methods Mol Biol 1998:105-116. PMID: 31250297. [PDF]
9. Banjade, S., Tang, S., Shah, Y.H., Emr, S.D. (2019) Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly. eLife 8. PMCID: PMC6663469. PMID: 31246173. [PDF]
2017
8. Jacobson, B.A., Sadiq, A.A., Tang, S., Jay-Dixon, J., Patel, M.R., Drees, J., Sorenson, B.S., Russell, S.J., Kratzke, R.A. (2017) Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma. Oncotarget 8(38):63096-63109. PMCID: PMC5609906. PMID: 28968974. [PDF]
2016
7. Tang, S., Buchkovich, N.J., Henne, W.M., Banjade, S., Kim, Y.J., Emr, S.D. (2016) ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis. eLife 5. PMCID: PMC4865371. PMID: 27074665. [PDF]
2015
6. Tang, S., Henne, W.M., Borbat, P.P., Buchkovich, N.J., Freed, J.H., Mao, Y., Fromme, J.C., Emr, S.D. (2015) Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments. eLife 4. PMCID: PMC4720517. PMID: 26670543. [PDF]
5. Patel, M.R., Jacobson, B.A., Ji, Y., Drees, J., Tang, S., Xiong, K., Wang, H., Prigge, J.E., Dash, A.S., Kratzke, A.K., Mesev, E., Etchison, R., Federspiel, M.J., Russell, S.J., Kratzke, R.A. (2015) Vesicular stomatitis virus expressing interferon-beta is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer. Oncotarget 6(32):33165-33177. PMCID: PMC4741756. PMID: 26431376. [PDF]
4. Jacobson, B.A., Chen, E.Z., Tang, S., Belgum, H.S., McCauley, J.A., Evenson, K.A., Etchison, R.G., Jay-Dixon, J., Patel, M.R., Raza, A., Saluja, A.K., D'Cunha, J., Kratzke, R.A. (2015) Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma. Genes Cancer 6(3-4):144-152. PMCID: PMC4426951. PMID: 26000097. [PDF]
3. Meng, S., Tian, T., Han, D., Wang, L., Tang, S., Meng, X., Li, Z. (2015) Efficient assembly of oligomannosides using the hydrophobically assisted switching phase method. Org Biomol Chem 13(24):6711-6722. PMID: 25967589. [PDF]
2013
2. Buchkovich, N.J., Henne, W.M., Tang, S., Emr, S.D. (2013) Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation. Dev Cell 27(2):201-214. PMID: 24139821. [PDF]
2009
1. Tang, S., Tang, X. (2009) Development of gaze following. Chin J Sch Health 30(11):1057-1058.